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Onco Checklist >> Multiple Myeloma Staging

 


HistologyResult
Bone marrow aspiration and biopsy, peripheral blood smears
 
Cytogenetics / molecular biology, if necessary to estimate prognosis 


Patient history
Result
 Weight loss (>10% in 6 months)   
 Night sweats (requiring change of clothes) 
 Fever (>38°C) without any other cause 


Physical examinationResult
 Lymph nodes, heart-/lung, abdominal examination, edema? Skin lesions? 
 Height and weight 
 Blood pressure and pulse 



Clinical chemistry Result
Proteins:
SERUM - Immunoglobulins quantitative (IgG, IgA, IgM), serum electropheresis, immune fixation, light chains, beta-2-microglobulin, albumin, total protein
24h-URINE - (total-)protein excretion, creatinine clearance, light chains, immune fixation
 
Electrolytes
Creatinine
Creatinine clearance (calculated)
Liver enzymes (AST; ALT; G-GT)
Bilirubin
ESR
Alk Phos
Coagulation parameters (incl. ATIII, D-dimers, fibrinogen)
LDH
CRP
 


VirologyResult
 HIV 1 and 2 
 Hepatitis B 
 Hepatitis C 



Imaging and further diagnosticsResult
Whole body X-ray "plasmacytoma" or whole body MRI 
Chest X-ray
 
Sonography of abdomen 
Echocardiography 
Spirometry
 
EKG 


StudiesResult
 Study inclusion possible?
yes no
 Study: 



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